2007 業績紹介

2007年

1. 成人および高齢者の精神・神経疾患の認知神経科学的研究

－論文－

  1. Doi R, Morita K, Shigemori M, Tokutomi T, Maeda H.: Characteristics of cognitive function in patients after traumatic brain injury assessed by visual and auditory event-related potentials. Am J Phys Med Rehabil 2007 Aug;86(8):641-9.
  2. Nishiura S, Morita K, Kurakake K, Igimi H, Maeda H.： Characteristics of left and right scanning in schizophrenia patients using exploratory eye movements: Comparison with healthy subjects. 　 Psychiatry Clin 2007;61:487-94.
  3. Nishiura S, Nakashima Y, Mori K, Kodama T, Hirai S, Kurakake K, Egami C, Morita K： A Life Span Study of Exploratory Eye Movements in Healthy Subjects: Gender Differences and Affective Influences. Kurume Med J 2007;54(3,4)65-72.
  4. Habukawa M, Uchimura N, Maeda M, Kotorii N, Maeda　H: Sleep Findings in Young Adult Patients with Posttraumatic Stress Disorder.　 Biol Psychiatry 　2007;62:1179-82.
  5. Hoeft F,　Ueno T, A L Reiss,　A Meyler,　S Whitfield-Gabrieli,　GH. Glover,　T A Keller, Kobayashi N,　P Mazaika,　B Jo,　M Adam Just,　John D.E. Gabrieli　:　Prediction of children's reading skills using behavioral, functional, and structural neuroimaging measures.　 Behav Neurosci　 2007;121:602-13.
  6. Terasaki M, Abe T, Miyagi N, Ogo E, Shigemori M: Feasibility and response to1-(4-amino-2-methyl-5-pyrimidynyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride chemotherapy with pre-treated procarbazine for elderly patients with newly diagnosed glioblastoma. J Neurooncol 2007;81:265-9.
  7. Sugita Y, Takase Y, Mori D, Tokunaga O, Nakashima A, Shigemori M: Endoglin (CD 105) is expressed on endothelial cells in the primary central nervous system lymphomas and correlates with survival. J Neurooncol 2007;82:249-56.
  8. Sugita Y, Komatani H, Ohshima K, Shigemori M, Nakashima A: Expression of cyclooxygenase-2 and vascular endothelial growth factor in primary central nervous system lymphomas. 　Oncol Rep 2007;18:617-22.
  9. Terasaki M, Ogo E, Fukushima S, Sakata K, Miyagi N, Abe T, Shigemori M: Impact of combination therapy with repeat surgery and temozolomide for recurrent or progressive glioblastoma multiforme: a prospective trial. Surg Neurol　 2007;68:250-4.

2. 成人および高齢者の精神・神経疾患の分子生物学的研究

－論文－

  1. Nguyen C, Nishi A, Kansy JW, Fernandez J, Hayashi K, Gillardon F, Hemmings HC Jr, Nairn AC, Bibb JA. : Regulation of protein phosphatase inhibitor-1 by cyclin-dependent kinase 5. J Biol Chem 2007;282:16511-20.
  2. Ahn J-H, Sung JY, McAvoy T, Nishi A, Janssens V, Goris J, Greengard P, Nairn AC. : The B"/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. Proc Natl Acad Sci USA 　2007;104:9876-81.
  3. Nguyen C, Hosokawa T, Kuroiwa M, Ip NY, Nishi A, Hisanaga S, Bibb JA. : Differential regulation of the Cdk5-dependent phosphorylation sites of inhibitor-1 and DARPP-32 by depolarization. J Neurochem 　2007;103:1582-93.
  4. Sotogaku N, Tully SE, Gama CI, Higashi H, Tanaka M, Hsieh-Wilson LC, Nishi A.: Activation of phospholipase C pathways by a synthetic chondroitin sulfate-E tetrasaccharide promotes neurite outgrowth of dopaminergic neurons. J Neurochem 2007;103:749-60.
  5. Kitaoka S, Furuyashiki T, Nishi A, Shuto T, Koyasu S, Matsuoka T, Miyasaka M, Greengard P, Narumiya S. : Prostaglandin E2 Amplifies Dopamine Receptor Signaling in the Striatum by Acting on Prostaglandin E Receptor Subtype EP1. J Neurosci 2007;27:12900-7.
  6. Sonomura T, Nakamura K, Furuta T, Hioki H, Nishi A, Yamanaka A, Uemura M, Kaneko T.: Expression of D1 but not D2 Dopamine Receptors in Striatal Neurons Producing Neurokinin B in rats. Eur J Neurosci 　2007;26:3093-103.
  7. Yamada H, Kuroki T, Nakahara T, Hashimoto K,Tsutsumi T, Hirano M, Maeda H： The dopamine D1 receptor agonist, but not the D2 receptor agonist, induces gene expression of Homer 1a in rat striatum and nucleus accumbens. Brain Res 　2007;1131:88-96.
  8. Kurokawa-Kuroda T, Ogata K, Suga R, Goto Y, Taniwaki T, Kira JI, Tobimatsu S: Altered soleus responses to magnetic stimulation in pure cerebellar ataxia. 　Clin Neurophysiol 2007;118(6):1198-203.
  9. Taniwaki. T, Okayama. A, Yoshiura. T, Togao. O, Nakamura. Y, Yamasaki. T, Ogata. K, Shigeto. K, Ohyagi. Y, Kira. J, Tobimatsu S: Age-related alterations of the functional interactions within the basal ganglia and cerebellar motor loops in vivo. 　Neuro　Image 　　2007;36(4):1263-76.
  10. Miura S, Kusumoto M, Noda K, Azuma K, Toda R, Honda S, Ayabe M, Aizawa H, Taniwaki T: Bell-shaped sensory impairments of all modalities in a neurosarcoidosis patient. Clin Neurol Neurosurg 　2007;109(9):794-8.
  11. Miura S, Kida H, Nishimura S, Noda K, Urano T, Honda S, Ayabe M Aizawa H, Taniwaki T: Unilateral tonic pupil in spinocerebellar ataxia without brainstem atrophy. Neurology Asia 　2007;12:131-3.
  12. Harmer　M, Tanaka G, Okamura　H, Steptoe　A, Tsuda A　：The Effects of Depressive Symptoms on Cardiovascular and Catecholamine Responses to the Induction of Depressive Mood. Biolo Psychol 2007;７4:20-25.
  13. Steptoe A, Tsuda A, Tanaka Y, Wardle J : Depressive symptoms, socioeconomic background, sense of control and cultural factors in university students from 23 countries. Brain Behav Immunity 2007;22(2):209-14.

3. 小児の精神・神経疾患の分子基盤解明と遺伝子治療に関する研究

－論文－

  1. Iwata S, Iwata O, --Matsuishi T(last author). : Abnormal white matter appearance on term FLAIR predict neuro-developmental outcome at 6 years old following preterm birth. Int J Devel Neuroscience 2007;89:523-30.
  2. Kawano G,Oshige K, Syutou S, Koteda Y, Yokoyama T, Kim B G, Mizuochi T, Nagai K, Matsuda K, Ohbu K, Matsuishi T: Benign infantile convulsions associated with mild gastroenteritis:A retrospective study of 39 cases including virological tests and efficacy of anticonvulsants. Brain Dev 2007;29(10):617-22.
  3. Koga Y, Akita Y, Nishioka J, Yatsuga S, Povalko N, Katayama K, Matsuishi T: MELAS and L-arginine therapy. Mitochondrion 2007;7(1-2):133-9.
  4. Indo HP, Davidson M, Yen HC, Suenaga S, Tomita K, Nishii T, Higuchi M, Koga Y, Ozawa T, Majima HJ: Evidence of ROS generation by Mitochondria in cells with impaired electron transport chain and mitochondrial DNA damage. Mitochondrion 2007;7(1,2):106-18.
  5. Tanaka M, Nishigaki Y, Fuku N, Ibi T, Sahashi K, Koga Y: Therapeutic potential of pyruvate therapy for mitochondrial diseases. Mitochondrion 2007;7(6):399-401.
  6. Itoh M, Ide S, Takashima S, Kudo S, Nomura Y, Segawa M, Kubota T, Mori H, Tanaka S, Horie H, Tanabe Y, Goto Y: Methyl CpG-binding protein 2 (a mutation of which causes Rett syndrome) directly regulates insulin-like growth factor binding protein 3 in mouse and human brains. J Neuropathol Exp Neurol 2007;66:117-23.
  7. Okoshi Y, Mizuguchi M, Itoh M, Oka A, Takashima S: Altered nestin expression in the cerebrum with periventricular leukomalacia. Pediatr Neurol 2007;36:170-4.
  8. Saitoh M, Sakakihara Y, Mizuguchi M, Itoh M, Takashima S, Iwamori M, Kamoshita S, Igarashi T: Increase of ceramide monohexoside and dipalmitoyl glycerophospholipids in the brain of Zellweger syndrome. Neurosci Lett 2007;417:165-70.
  9. Segawa Y, Itokazu N, Hirose A, Nakagawa S, Takashima S: A case of partial14q- with facial features of holoprosencephaly and hydranencephaly. 　Pediatric Neurology 　 2007;37:51-54.
  10. Chen XH, Minatogichi S, Kosai K, Yuge K, Takahashi T, Arai M, Wang N, Misao Y, Lu C, Onogi H, Kobayashi H, Yasuda S, Ezaki M, Ushikoshi H, Takemura G, Fujiwara T, Fujiwara H：　In vivo hepatocyte growth factor gene transfer reduces myocardial ischemia-reperfusion injury through its multiple actions. J Card Fail 2007；13(10):874-883.
  11. Ozono S, Saeki T, Mantani T, Ogata T, Okamura H, Yamawaki S. Factors Related to Posttraumatic Stress in Adolescent Survivors of Childhood Cancer and their Parents.　 Support Care Cancer　2007;15(3):309-17.
  12. Yoshino M, Watanabe Y, Tokunaga Y, Harada E, Fujii C, Numata S, Harada M, Tajima A, Ida H. Roles of some cytokines in bone remodeling and hematopoiesis in Gaucher disease. Pediatr Int 2007;49:1-7.
  13. Uematsu M, Sakamoto O, Sugawara N, Kumagai N, Morimoto T, Yamaguchi S, Hasegawa Y, Kobayashi H, Ihara K, Yoshino M, Watanabe Y, Inokuchi T, Yokoyama T, Kiwaki K, Nakamura K, Endo F, Tsuchiya S, Ohura T. Novel mutations in five Japanese patients with 3-methylcrotonyl-CoA carboxylase deficiency. J Hum Genet 2007;52:1040-3.
  14. Samejima H, Torii C, Kosaki R, Kurosawa K, Yoshihashi H, Muroya K, Okamoto N, Watanabe Y, Kosho T, Kubota M, Matsuda O, Goto M, Izumi K, Takahashi T, Kosaki K. Screening for Alagille syndrome mutations in the JAG1 and NOTCH2 genes using denaturing high-performance liquid chromatography. Genet Test 2007;11:216-27.