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Olfactory marker protein interacts with adenosine nucleotide derivatives.
Biochem Biophys Rep, 25, 100887, 2021.3
10.1016/j.bbrep.2020.100887pub med
Olfactory Marker ProteinはcAMPをバッファーする.
Aroma Research, 21(4), 62-63, 2020.11
Olfactory marker protein contributes to the evaluation of odour values by olfactory glomerular processing.
Neurosci Lett, 739, 135445, 2020.11
doi: 10.1016/j.imu.2020.100442pub med
Virus database annotations assist in tracing information on patients infected with emerging pathogens.
Inform Med Unlocked, 21, 100442, 2020.10
doi: 10.1016/j.imu.2020.100442pub med
心電図, 40, 95-100, 2020.8
doi: 10.5105/jse.40.95
Expression of the pacemaker channel HCN4 in excitatory interneurons in the dorsal horn of the murine spinal cord.
Mol Brain, 13, 127, 2020.9
doi: 10.1186/s13041-020-00666-6pub med
Olfactory marker protein elevates basal cAMP concentration.
Biochem Biophys Res Commun, 531, 203-208, 2020.10
doi: 10.1016/j.bbrc.2020.07.087pub med
Olfactory marker protein captures cAMP produced via Gαs-protein-coupled receptor activation.
Biochem Biophys Res Commun, 529, 341-346, 2020.8
doi: 10.1038/s41467-020-15917-2pub med
久留米医会誌, 83(6), 113-123, 2020.6
Olfactory marker protein directly buffers cAMP to avoid depolarization-induced silencing of olfactory receptor neurons.
Nat Commun, 11, 2188, 2020.5
doi: 10.1038/s41467-020-15917-2pub med
Anti-PDHA1 antibody is detected in a subset of patients with schizophrenia.
Sci Rep, 10(1), 7906, 2020.5
doi: 10.1038/s41598-020-63776-0pub med
Surgical outcomes and unique histological features of tonsils after tonsillectomy in adults with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis syndrome.
Auris Nasus Larynx, 47(2), 254-261, 2020.4
doi: 10.1016/j.anl.2019.08.009pub med
Properties of SK3 channel-expressing PDGFRα(+) cells in the rodent urinary bladder.
Eur J Pharmacol, 860, 172552, 2019.10
doi: 10.1016/j.ejphar.2019.172552pub med
Mucosa-Dependent, Stretch-Sensitive Spontaneous Activity in Seminal Vesicle.
In: Smooth Muscle Spontaneous Activity. Advances in Experimental Medicine and Biology, vol 1124, Springer, pp. PP 217-231
doi: 10.1007/978-981-13-5895-1_9pub med
Overexpression of the HCN2 channel increases the arrhythmogenicity induced by hypokalemia.
J Physiol Sci, 69(4), 653-660
doi: 10.1007/s12576-019-00684-7pub med
Olfactory receptor neurons express olfactory marker protein but not calpain 5 from the same genomic locus.
Mol Brain, 12(1), 54
doi: 10.1186/s13041-019-0474-z pub med
SCIENCE TOPICS ―内向き整流性カリウムチャネル透過性の細胞外K+濃度依存性は、細胞外Na+による競合的ブロックに起因する~高カリウム血症で心室再分極速度が上昇するメカニズム~.
日本生理学会誌, 80(4), 83
External K+ dependence of strong inward rectifier K+ channel conductance is caused not by K+ but by competitive pore blockade by external Na+.
J Gen Physiol, 150(7), 977-989
doi: 10.1085/jgp.201711936 pub med
HCN4-overexpressing mouse embryonic stem cell-derived cardiomyocytes Generate a new rapid rhythm in rats with bradycardia.
Int Heart J, 59(3), 601-606
doi: 10.1536/ihj.17-241pub med
HCN4 pacemaker channels attenuate the parasympathetic response and stabilize the spontaneous firing of the sinoatrial node.
J Physiol, 596(5), 809-825
doi: 10.1113/JP275303 pub med
Dual expression of constitutively active Gαs-protein-coupled receptors differentially establishes the resting activity of the cAMP-gated HCN2 channel in a single compartment.
Biochem Biophys Res Commun, 494(1-2), 76-81
doi: 10.1016/j.bbrc.2017.10.082 pub med

Role of mucosa in generating spontaneous activity in the guinea pig seminal vesicle.
J Physiol, 595(14), 4803-4821
doi: 10.1113/JP273872 pub med

日本医事新報, No.4862, 61-62


Regeneration of dermal patterns from the remaining pigments after surgery in Eublepharis macularius (a case report).
BMC Veterinary Research, 12, 139
doi: 10.1186/s12917-016-0765-x pub med

Regenerative therapy for vestibular disorders using human induced pluripotent stem cells (iPSCs): neural differentiation of human iPSC-derived neural stem cells after in vitro transplantation into mouse vestibular epithelia.
Acta Otolaryngol, 136(10), 999-1005
doi: 10.1080/00016489.2016.1183169 pub med

The hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contain multiple S-palmitoylation sites.
J Physiol Sci, 66(3), 241-248
doi: 10.1007/s12576-015-0420-5 pub med

Clinical concentrations of local anesthetics bupivacaine and lidocaine differentially inhibit human Kir2.x inward rectifier K+ channels.
Anesth Analg, 122(4), 1038-1047
doi: 10.1213/ANE.0000000000001137 pub med

Neuronal and glial expression of inward rectifier potassium channel subunits Kir2.x in rat dorsal root ganglion and spinal cord.
Neurosci Lett, 617, 59-65
doi:10.1016/j.neulet.2016.02.007 pub med

Effects of silodosin and tamsulosin on the seminal vesicle contractile response.
LUTS, 8(1), 55-61
doi: 10.1111/luts.12072 pub med


Ectopic automaticity induced in ventricular myocytes by transgenic overexpression of HCN2.
J Mol Cell Cardiol, 80, 81-89
doi:10.1016/j.yjmcc.2014.12.019pub med

臨と研 92(6), 134-137

Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias.
Sci Rep, 5, 11204
doi:10.1038/srep11204 pub med

Renal nerve-mediated erythropoietin release confers cardioprotection during remote ischemic preconditioning.
Circ J, 79(7), 1557-1567
doi:10.1253/circj.CJ-14-1171 pub med

Genotype-dependent differences in age of manifestation and arrhythmia complications in short QT syndrome.
Int J Cardiol, 190, 393-402
doi:10.1016/j.ijcard.2015.04.090 pub med

Enhancement of spontaneous activity by HCN4 overexpression in mouse embryonic stem cell-derived cardiomyocytes - a possible biological pacemaker.
PloS One, 10(9), e0138193
doi:10.1371/journal.pone.0138193 pub med


Persistent α1-adrenergic receptor function in the nucleus locus coeruleus causes hyperexcitability in AD/HD model rats.
J Neurophysiol, 111(4), 777-786
doi: 10.1152/jn.01103.2012 pub med


5章 消化吸収 5-3 消化管運動. 『新訂 生理学実習書』, 南江堂, pp. 98-105

心電図, 33(2), 179-185

Increased expression of HCN channels in the ventricular myocardium contributes to enhanced arrhythmicity in mouse failing hearts.
J Am Heart Assoc, 2(3), e000150
doi: 10.1161/JAHA.113.000150 pub med

久留米医会誌, 76(3~5), 126-134


第1章 心筋の電気生理 8 過分極誘発陽イオンチャネル/HCN.
『不整脈学』, 南江堂, pp. 29-31

久留米医会誌, 75(5・6), 173-179

Arrhythmogenic coupling between the Na+–Ca2+ exchanger and inositol 1,4,5-triphosphate receptor in rat pulmonary vein cardiomyocytes.
J Mol Cell Cardiol, 52(5), 988-997

Function and expression pattern of TRPM8 in bladder afferent neurons associated with bladder outlet obstruction in rats.
Auton Neurosci, 164(1-2), 27-33
Edaravone attenuates impairment of synaptic plasticity in granule cell layer of the dentate gyrus following traumatic brain injury.
Kurume Med J, 58(2), 47-58
『なぜこうなる? 心電図 [新装版]―波形の成立メカニズムを考える―』.
Pathophysiological remodeling of mouse cardiac myocytes expressing dominant negative mutant of neuron restrictive silencing factor.
Circ J, 74(12), 2712-2719
久留米医会誌, 73(3・4), 69-80
久留米医会誌, 73(3・4), 81-89
久留米医会誌, 73(3・4), 90-98
Functional molecular imaging of ILK-mediated Akt/PKB signaling cascades and the associated role of β-parvin.
J Cell Sci, 123(5), 747-755
Methylphenidate enhances inhibitory synaptic transmission by increasing the content of norepinephrine in the locus coeruleus of juvenile rats.
Kurume Med J, 57(1,2), 29-38
神経外傷, 32(2), 61-67
Mild hypothermia prevents post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 pyramidal neurons.
Kurume Med J, 56(3,4), 49-59
Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder.
Neurosci Res, 65(3), 245-251
生体の科学, 60(5), 430-431
p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.
Circ Res, 105(8), 746-754
T-type Ca2+ channel blockade prevents sudden death in mice with heart failure.
Circulation, 120(9), 743-752
The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2.
Cardiovasc Res, 83(4), 682-687
Self-contained induction of neurons from human embryonic stem cells.
PLoS One, 4(7), e6318
Making educational DVD for the faculty development in the PBL tutorial.
The 2nd International PBL symposium 2009 "What are we learning about learning?", 634-640
久留米医会誌, 71(9-12), 341-348
Spinophilin inhibits the binding of RGS8 to M1-mAChR but enhances the regulatory function of RGS8.
Biochem Biophys Res Commun, 377(1), 200-204
Diazepam attenuates the post-traumatic hyperactivity of excitatory synapses in rat hippocampal CA1 neurons.
Neurosci Res, 62(3), 195-205
久留米医会誌, 70(11・12), 353-360
『なぜこうなる? 心電図 ―波形の成立メカニズムを考える―』.
Hyperpolarization-activated cyclic nucleotide-gated channels and T-type calcium channels confer automaticity of embryonic stem cell-derived cardiomyocytes.
Stem Cells, 25(11), 2712-2719

第12章 糖尿病.
『高齢者医療ハンドブック』, 九州大学出版会, pp. 55-61

第19章 前立腺肥大症.
『高齢者医療ハンドブック』, 九州大学出版会, pp. 94-98
第20章 過活動膀胱.
『高齢者医療ハンドブック』, 九州大学出版会, pp. 99-103
11 神経系の構造と機能.
『看護師国家試験 解剖生理学クリアブック』, 医学書院, pp. 162-181
心電図, 27(Suppl 3), 15-28
Clin Neurosci, 25(4), 395-396
久留米医会誌, 70(3・4), 71-77
久留米大学医学部附属臨床検査専門学校紀要, 第15号, 60-62
久留米医会誌, 70(1・2), 1-7
NRSF regulates the developmental and hypertrophic changes of HCN4 transcription in rat cardiac myocytes.
Biochem Biophys Res Commun, 353(1), 67-73
chapter 21 診療所における小児救急への対応.
『小児救急学習用テキスト(原著第4版)』, 診断と治療社, pp. 612-644
神経外傷, 29(1), 38-43
A distinct group of non-cholinergic neurons along the mid-line of the septum and within the rat medial septal nucleus.
Neurosci Lett, 410(1), 20-24
Alternative splicing of RGS8 gene changes the binding property to the M1 muscarinic receptor to confer receptor type-specific Gq regulation.
J Neurochem, 99(6), 1505-1516
Effect of traumatic brain injury on hippocampal CA1 pyramidal neurons in rats.
Chin J Trauma, 22(11), 843-847
Effects of lateral fluid percussion injury of brain on the bilateral GFAP expression in hippocampus and synaptic transmission in hippocampal CA1 area of rats.
Chin J Neurosurg Dis Res, 5(5), 389-393
Dopamine presynaptically depresses fast inhibitory synaptic transmission via D4 receptor-protein kinase A pathway in the rat dorsolateral septal nucleus.
J Neurophysiol, 96(2), 591-601
Facilitation of glutamatergic synaptic transmission in hippocampal CA1 area of rats with traumatic brain injury.
Neurosci Lett, 401(1-2), 136-141
久留米医会誌, 69(2~4), 113-123
第Ⅱ編 神経細胞と筋細胞の生理学 2.興奮性組織:神経.
『ギャノング生理学(原書第22版)』, 丸善株式会社, pp. 53-66
Edaravone effectively improve the neuronal dysfunction induced by lateral fluid percussion injury in rats.
Neurotrauma Res, 18, 35-40
High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations.
J Am Coll Cardiol, 46(11), 2100-2106
Pathophysiological significance of T-type Ca2+ channels: transcriptional regulation of T-type Ca2+ channel--regulation of CACNA1H by neuron-restrictive silencer factor.
J Pharmacol Sci, 99(3), 211-213
Prospective identification of cardiac progenitors by a novel single cell-based cardiomyocyte induction.
FASEB J, 19(11), 1534-1536
Effects of emodin on synaptic transmission in rat hippocampal CA1 pyramidal neurons in vitro.
Neuropharmacology, 49(1), 103-111
Properties of dopamine-induced outward current in neurons of the rat dorsolateral septal nucleus.
Kurume Med J, 52(1,2), 57-62
Effects and wavelet spectral entropy analysis of rhubarb extracts rhein on synaptic transmission in rat hippocampal ca1 area in vitro.
Chin Med J, 118(10), 817-823
脳と発達, 37(1), 31-38
Properties of dopamine-induced outward current in neurons of the rat dorsolateral septal nucleus.
Kurume Med J, 52(1,2), 57-62
Molecular cloning and characterization of a new RGS protein of Medaka.
Itoh M, Nagatomo K, Kubo Y, Sugimoto M, Saitoh O
Gene, 345(2), 165-171
Hyperexcitability in the hippocampal CA1 is suppressed by diazepam administration in rats with fluid percussion injury.
Neurotrauma Res, 17, 9-12
Mechanical unloading improves intracellular Ca2+ regulation in rats with doxorubicin-induced cardiomyopathy.
J Am Coll Cardiol, 44(11), 2239-2246
Effects of milnacipran on the inhibitory postsynaptic potential in neurons of the rat locus coeruleus.
Kurume Med J, 51(3,4), 185-191
Effects of adenosine and ATP on the membrane potential and synaptic transmission in neurons of the rat locus coeruleus.
Kurume Med J, 51(2), 109-123
5-Hydroxytryptamine 1B receptors mediate presynaptic inhibition of monosynaptic IPSC in the rat dorsolateral septal nucleus.
Neurosci Res, 48(3), 229-238
DARPP-32: An integrator of neurotransmission.
Annu Rev Pharmacol Toxicol 44: 269-296
Mechanical unloading improves intracellular Ca2+ regulation in rats with doxorubicin-induced cardiomyopathy.
J Am Coll Cardiol 44(11): 2239-2246
Distinct profiles of refilling of inhibitory neurotransmitters into presynaptic terminals projecting to spinal neurones in immature rats.
J Physiol 560(2): 469-478
NRSF regulates the fetal cardiac gene program and maintains normal cardiac structure and function.
EMBO J, 22(23), 6310-6321
泌尿器外科, 16(11), 1147-1152
日本LD学会第12回大会発表論文集, 295-296
Effects of serotonin and dopamine in neurons of the dorsolateral septal nucleus.
J Brain Sci, 29, 21-25
Monocarboxylate transporters contribute to the adaptation of neuronal activity to repeated glucose deprivation in the rat lateral septal nucleus.
Synapse, 49(2), 97-105
Verapamil, a Ca2+ entry blocker, targets the pore-forming subunit of cardiac type KATP channel (Kir6.2).
J Cardiovasc Pharmacol, 42(2), 161-168
Protective role of heparin/heparan sulfate on oxalate-induced changes in cell morphology and intracellular Ca2+.
Urol Res, 31(3), 198-206
Contribution of nitric oxide to the depression of neuronal activity induced by temperature increase in the rat hippocampal CA1 area.
Neurosci Lett, 344(3), 153-156
The electrophysiological properties of spontaneously beating pacemaker cells isolated from mouse sinoatrial node.
J Physiol, 550(1), 169-180
L-Arginine enhances heat-induced depression of neuronal activity in the rat hippocampal CA1 area.
Kurume Med J, 50(1,2), 27-34
Distribution of regulator of G protein signaling 8 (RGS8) protein in the cerebellum.
Cerebellum, 2(2), 154-160
Effects of emodin on synaptic transmission in rat hippocampal CA1 area in vitro.
2003' Xian International Neurosurgical Academic Forum 論文集, 151-159
久留米医会誌, 66(1・2), 37-46
Pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid can antagonize the purinoceptor-mediated inhibition of M-current in bullfrog sympathetic neurons.
Neurosci Lett, 337(2), 93-96
Regulation of cardiac inwardly rectifying potassium channels by membrane lipid metabolism.
Prog Biophys Mol Biol, 81(1), 67-79
Effects of methylphenidate on the inhibitory postsynaptic potential in rat locus coeruleus neurons.
Kurume Med J, 49(4), 185-190
腎尿細管上皮細胞に存在するheparan sulfate (HS)/heparan sulfate proteoglycan (HSPG, syndecan-1)の機能解析.
日尿結石誌, 1(1), 110-113
Activation of presynaptic 5-hydroxytryptamine 2A receptors facilitates excitatory synaptic transmission via protein kinase C in the dorsolateral septal nucleus.
J Neurosci, 22(17), 7509-7517
Hyperexcitability of hippocampal CA1 neurons after fluid percussion injury of the rat cerebral cortex.
Neurosci Lett, 329(3), 305-308
医教育, 33(4), 269-272
α1-Adrenoceptor-mediated breakdown of phosphatidylinositol 4,5-bisphosphate inhibits pinacidil-activated ATP-sensitive K+ currents in rat ventricular myocytes.
Circ Res, 91(3), 232-239
Alternative splicing of RGS8 gene determines inhibitory function of receptor type-specific Gq signaling.
Proc Natl Acad Sci USA, 99(15), 10138-10143
Effects of fluid percussion injury on the neuronal activity in the hippocampal CA1 area and the dentate gyrus of the rat.
Kurume Med J, 49(1・2), 15-26
Effects of temperature increase on the propagation of presynaptic action potentials in the pathway between the Schaffer collaterals and hippocampal CA1 neurons.
Neurosci Res, 42(3), 175-185
Effects of methylphenidate on the membrane potential and current in neurons of the rat locus coeruleus.
J Neurophysiol, 87(3), 1206-1212
第Ⅱ編 神経細胞と筋細胞の生理学 2. 興奮性組織:神経.
『医科生理学展望(原書20版)』, 丸善株式会社, pp. 55-68
特集:内科-100年のあゆみ(循環器) II. 日本人の貢献
9. ATP感受性K+チャネル.
L日内会誌, 91(3), 865-867
Role of KCNQ1 in the cell swelling-induced enhancement of the slowly activating delayed rectifier K+ current.
Jpn J Physiol, 52(1), 31-39
Intrinsic factors involved in the depression of neuronal activity induced by temperature increase in rat hippocampal neurons.
Kurume Med J, 48(4), 295-306
Evidence for a single nucleotide polymorphism in the KCNQ1 potassium channel that underlies susceptibility to life-threatening arrhythmias.
J Cardiovasc Electrophysiol, 12(11), 1223-1229
Determinants of activation kinetics in mammalian hyperpolarization-activated cation channels.
J Physiol, 537(1), 93-100
質疑応答【生理学】 中枢神経細胞の正常な機能と血糖値の関係.
日医新報, 4044, 93
Optical recording of the spatiotemporal propagation of neuronal excitation in the rat hippocampal CA2-CA1 pathway.
Kurume Med J, 48(3), 205-210
Effects of 5-hydroxytryptamine on the excitatory postsynaptic potential in neurons of the rat dorsolateral septal nucleus.
Kurume Med J, 48(3), 247-250
RGS8 protein is distributed in dendrites and cell body of cerebellar Purkinje cell.
Biochem Biophys Res Commun, 287(1), 223-228
Activation of inhibitory pathways suppresses the induction of long-term potentiation in neurons of the rat lateral septal nucleus.
Neuroscience, 105(2), 343-352
5-Hydroxytryptamine facilitates spatiotemporal propagation of optical signals in the hippocampal-septal pathway.
Neurosci Res, 40(3), 265-272
Dual action of ZD6169, a novel K+ channel opener, on ATP-sensitive K+ channels in pig urethral myocytes.
Br J Pharmacol, 133(1), 154-164
Characterization of outward currents induced by 5-HT in neurons of rat dorsolateral septal nucleus.
J Neurophysiol, 85(4), 1453-1460
Characterization and subcellular localization of KCNQ1 with a heterozygous mutation in the C terminus.
J Mol Cell Cardiol, 33(2), 197-207
Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates KATP channels in guinea-pig ventricular myocytes.
Pflügers Arch, 441(2-3), 200-207
Angiotensin II type 1 receptor blockade abolishes specific KATP channel gene expression in rats with myocardial ischemia.
J Mol Cell Cardiol, 32(12), 2239-2247
The effects of caffeine on ATP-sensitive K+ channels in smooth muscle cells from pig urethra.
Br J Pharmacol, 131(3), 505-513
5-Hydroxytryptamine-induced outward currents mediated via 5-HT1A receptors in neurons of the rat dorsolateral septal nucleus.
Neurosci Res, 37(4), 307-314
The properties of the Kir6.1-6.2 tandem channel co-expressed with SUR2A.
Pflügers Arch, 440(5), 692-698
久留米医会誌, 63(6-7), 131-139
久留米医会誌, 63(6-7), 131-139
Effects of corticosteroids on synaptic transmission in rat dorsolateral septal nucleus.
Jpn J Physiol, 50(2), 267-272
5-Hydroxytryptamine modulates synaptic transmission in the hippocamposeptal pathway.
In: Slow Synaptic Responses and Modulation, Springer, pp. 403-409
Modulation of synaptic transmission in the autonomic nervous system.
In: Slow Synaptic Responses and Modulation, Springer, pp. 375-385
Modulation of the induction of LTP of excitatory hippocamposeptal transmission by GABAB receptor activation in rat lateral septal nucleus (LSN) neurons in vitro.
In: Slow Synaptic Responses and Modulation, Springer, pp. 318-319

The dawn and foundation of slow synaptic potentials and modulation.
In: Slow Synaptic Responses and Modulation, Springer, pp. 1-14