実績紹介



2021年度の実績はResearch Report 2021をご覧ください。

  • がんワクチン部門
  • 肝癌部門
  • 分子標的部門
2020
1
Yoshida N., Yamada K., Ohshima K. Comprehensive genomic analysis identifying heterogeneity in peripheral T-cell lymphoma. Cancer Sci, 112, 4, 1339-1347, 2021.
2
Yano J., Kaida Y., Maeda T., Hashida R., Tonan T., Nagata S., Hazama T., Nakayama Y., Ito S., Kurokawa Y., Otome T., Shibata R., Tashiro K., Kakuma T., Matsuse H., Fukami K. l-carnitine supplementation vs cycle ergometer exercise for physical activity and muscle status in hemodialysis patients: A randomized clinical trial. Ther Apher Dial, 25, 3, 304-313, 2021.
3
Yamada K., Miyoshi H., Yoshida N., Shimono J., Sato K., Nakashima K., Takeuchi M., Arakawa F., Asano N., Yanagida E., Seto M., Ohshima K. Human T-cell lymphotropic virus HBZ and tax mRNA expression are associated with specific clinicopathological features in adult T-cell leukemia/lymphoma. Mod Pathol, 34, 2, 314-326, 2021.
4
Waki K., Yokomizo K., Kawano K., Tsuda N., Komatsu N., Yamada A. Integrity of plasma cell-free DNA as a prognostic factor for vaccine therapy in patients with endometrial cancer. Mol Clin Oncol, 14, 2, 29, 2021.
5
Tse K. Y., Domingo E. J., Konar H., Kumarasamy S., Pariyar J., Tjokroprawiro B. A., Ushijima K., Inthasorn P., Tan A. L., Wilailak S. COVID-19 and gynecological cancers: Asia and Oceania Federation of Obstetrics and Gynecology oncology committee opinion. J Obstet Gynaecol Res, 47, 5, 1643-1650, 2021.
6
Tominaga J., Iwasawa T., Murota M., Arakawa H., Johkoh T., Yamano Y., Zaizen Y., Ichikado K., Hashisako M., Kondoh Y., Kataoka K., Okamoto M., Fujimoto K., Fukuoka J. Computed tomography findings of current nonspecific interstitial pneumonia based on the 2013 updated classification of idiopathic interstitial pneumonias: What is a characteristic of previously diagnosed nonspecific interstitial pneumonia excluded from the updated classification. Jpn J Radiol, 39, 1, 47-55, 2021.
7
Toh U., Takenaka M., Iwakuma N., Akagi Y. Clinical outcomes of patients after nipple-sparing mastectomy and reconstruction based on the expander/implant technique. Surg Today, 51, 6, 862-871, 2021.
8
Tanoue S., Endo H., Hiramatsu M., Matsumaru Y., Matsumoto Y., Sato K., Tsuruta W., Sato M., Hirohata M., Abe T., Kiyosue H. Delineability and anatomical variations of perforating arteries from normal vertebral artery on 3D DSA: implications for endovascular treatment of dissecting aneurysms. Neuroradiology, 63, 4, 609-617, 2021.
9
Takeshige N., Uchikado H., Nakashima D., Negoto T., Nagase S., Yoshitomi M., Sakata K., Morioka M. Endoscopic third ventriculostomy for myelomeningocele-related hydrocephalus after shunt failure: Long-term outcome in a series of 8 patients. Clin Neurol Neurosurg, 201, 106406, 2021.
10
Takehara K., Matsumoto T., Hamanishi J., Hasegawa K., Matsuura M., Miura K., Nagao S., Nakai H., Tanaka N., Tokunaga H., Ushijima K., Watari H., Yokoyama Y., Kase Y., Sumino S., Suri A., Itamochi H., Takeshima N. Phase 2 single-arm study on the safety of maintenance niraparib in Japanese patients with platinum-sensitive relapsed ovarian cancer. J Gynecol Oncol, 32, 2, e21, 2021.
11
Takeda M., Shimokawa M., Nakamura A., Nosaki K., Watanabe Y., Kato T., Hayakawa D., Tanaka H., Takahashi T., Kogure Y., Tachihara M., Fujimoto D., Yamaguchi K., Hamaguchi N., Okamoto I., Azuma K., Hasegawa K., Yamamoto N., Nakagawa K. A Phase II Study to Assess the Efficacy of Osimertinib in Patients With EGFR Mutation-positive NSCLC Who Developed Isolated CNS Progression (T790M-negative or Unknown) During First- or Second-generation EGFR-TKI or Systemic Disease Progression (T790M-negative) After Treatment With First- or Second-generation EGFR-TKI and Platinum-based Chemotherapy (WJOG12819L). Clin Lung Cancer, 2021.
12
Tajiri K., Sudo T., Ishi K., Kawahara A., Nagasu S., Shimomura S., Yuge K., Katagiri M., Yomoda T., Fujiyoshi K., Kenichi K., Ohchi T., Yoshida T., Mizobe T., Fujita F., Akiba J., Akagi Y. Investigation of clinicopathological characters and gene expression features in colorectal signet-ring cell carcinoma utilizing CMS classification. Mol Clin Oncol, 14, 5, 98, 2021.
13
Shimohira M., Kondo H., Ogawa Y., Kawada H., Koganemaru M., Ikeda O., Yamamoto A., Komada T., Tanoue S., Muraoka N., Tanikake M., Hayashi S., Yamamoto S., Sato T., Mizunuma K., Ganaha F., Murakami Y., Ishiguchi T. Natural History of Unruptured Visceral Artery Aneurysms Due to Segmental Arterial Mediolysis and Efficacy of Transcatheter Arterial Embolization: A Retrospective Multiinstitutional Study in Japan. AJR Am J Roentgenol, 216, 3, 691-697, 2021.
14
Shimohira M., Kiyosue H., Osuga K., Gobara H., Kondo H., Nakazawa T., Matsui Y., Hamamoto K., Ishiguro T., Maruno M., Sugimoto K., Koganemaru M., Kitagawa A., Yamakado K. Location of embolization affects patency after coil embolization for pulmonary arteriovenous malformations: importance of time-resolved magnetic resonance angiography for diagnosis of patency. Eur Radiol, 2021.
15
Sato F., Ono T., Kawahara A., Matsuo K., Kondo R., Sato K., Akiba J., Kawaguchi T., Kakuma T., Chitose S. I., Umeno H., Yano H. Prognostic Value of Tumor Proportion Score in Salivary Gland Carcinoma. Laryngoscope, 131, 5, E1481-e1488, 2021.
16
Sakata K., Nagata Y., Takeshige N., Kikuchi J., Shikata M., Ashida K., Nomura M., Morioka M. Early postoperative prediction of both disease remission and long-term disease control in acromegaly using the oral glucose tolerance test. Hormones (Athens), 2021.
17
Sakai K., Takahama T., Shimokawa M., Azuma K., Takeda M., Kato T., Daga H., Okamoto I., Akamatsu H., Teraoka S., Ono A., Ohira T., Yokoyama T., Yamamoto N., Nakagawa K., Nishio K. Predicting osimertinib-treatment outcomes through EGFR mutant-fraction monitoring in the circulating tumor DNA of EGFR T790M-positive patients with non-small cell lung cancer (WJOG8815L). Mol Oncol, 15, 1, 126-137, 2021.
18
Oya S., Morishige S., Ozawa H., Sasaki K., Semba Y., Yamasaki Y., Nakamura T., Aoyama K., Seki R., Mouri F., Osaki K., Miyamoto T., Maeda T., Nagafuji K. Beneficial tyrosine kinase inhibitor therapy in a patient with relapsed BCR-ABL1-like acute lymphoblastic leukemia with CCDC88C-PDGFRB fusion. Int J Hematol, 113, 2, 285-289, 2021.
19
Nanashima A., Tominaga K., Yonei A., Sekiya R., Oshikawa S., Sato Y., Wake N., Akiba J. A rare case of intrahepatic cholangiocarcinoma with tumor thrombus in the bile duct. Clin J Gastroenterol, 14, 1, 275-282, 2021.
20
Nakahara Y., Matsutani T., Igarashi Y., Matsuo N., Himuro H., Saito H., Yamada K., Murotani K., Hoshino T., Azuma K., Sasada T. Clinical significance of peripheral TCR and BCR repertoire diversity in EGFR/ALK wild-type NSCLC treated with anti-PD-1 antibody. Cancer Immunol Immunother, 2021.
21
Motohashi T., Yabuno A., Michimae H., Ohishi T., Nonaka M., Takano M., Nishio S., Fujiwara H., Fujiwara K., Kondo E., Sugiyama T., Tabata T. Randomized phase III trial comparing pegylated liposomal doxorubicin (PLD) at 50 mg/m² versus 40 mg/m² in patients with platinum-refractory and -resistant ovarian carcinoma: the JGOG 3018 Trial. J Gynecol Oncol, 32, 1, e9, 2021.
22
Morishige S., Miyamoto T., Eto T., Uchida N., Kamimura T., Miyazaki Y., Ogawa R., Okumura H., Fujisak T., Iwasaki H., Kawano N., Wake A., Ohta T., Takamatsu Y., Kurokawa T., Ito Y., Maeda T., Akashi K., Nagafuji K. Clinical features and chromosomal/genetic aberration in adult acute lymphoblastic leukemia in Japan: results of Fukuoka Blood & Marrow Transplant Group Studies ALL MRD 2002 and 2008. Int J Hematol, 113, 6, 815-822, 2021.
23
Matsuo N., Azuma K., Kojima T., Ishii H., Tokito T., Yamada K., Hoshino T. Comparative incidence of immune-related adverse events and hyperprogressive disease in patients with non-small cell lung cancer receiving immune checkpoint inhibitors with and without chemotherapy. Invest New Drugs, 2021.
24
Matsuo K., Nishio S., Matsuzaki S., Machida H., Mikami M. Hospital volume-outcome relationship in vulvar cancer treatment: a Japanese Gynecologic Oncology Group study. J Gynecol Oncol, 32, 2, e24, 2021.
25
Matsuo K., Nishio S., Matsuzaki S., Iwase H., Kagami S., Soeda S., Usui H., Nishikawa R., Mikami M., Enomoto T. Surgical margin status and recurrence pattern in invasive vulvar Paget’s disease: A Japanese Gynecologic Oncology Group study. Gynecol Oncol, 160, 3, 748-754, 2021.
26
Konno Y., Asano H., Shikama A., Aoki D., Tanikawa M., Oki A., Horie K., Mitsuhashi A., Kikuchi A., Tokunaga H., Terao Y., Satoh T., Ushijima K., Ishikawa M., Yaegashi N., Watari H. Lymphadenectomy issues in endometrial cancer. J Gynecol Oncol, 32, 2, e25, 2021.
27
Kobayashi E., Kanao H., Takekuma M., Nishio S., Kojima-Chiba A., Tozawa A., Yamaguchi S., Takeshima N., Nakatani E., Mikami M. A retrospective assessment of the safety and efficacy of laparoscopic radical hysterectomy in Japan during the early years following its introduction: a Japanese Gynecologic Oncology Group study (JGOG1081S). Int J Clin Oncol, 26, 2, 417-428, 2021.
28
Ko R., Shukuya T., Imamura C. K., Tokito T., Shimada N., Koyama R., Yamada K., Ishii H., Azuma K., Takahashi K. Phase I study of afatinib plus bevacizumab in patients with advanced non-squamous non-small cell lung cancer harboring EGFR mutations. Transl Lung Cancer Res, 10, 1, 183-192, 2021.
29
Kawaguchi T., Ono T., Sato F., Kawahara A., Kakuma T., Akiba J., Sato K., Chitose S. I., Umeno H. CD8+ T Cell Infiltration Predicts Chemoradiosensitivity in Nasopharyngeal or Oropharyngeal Cancer. Laryngoscope, 131, 4, E1179-e1189, 2021.
30
Kanno H., Goto Y., Sasaki S., Fukutomi S., Hisaka T., Fujita F., Akagi Y., Okuda K. Geriatric nutritional risk index predicts prognosis in hepatocellular carcinoma after hepatectomy: a propensity score matching analysis. Sci Rep, 11, 1, 9038, 2021.
31
Kajiwara S., Hasegawa Y., Negoto T., Orito K., Kawano T., Yoshitomi M., Sakata K., Takeshige N., Yamakawa Y., Jono H., Saito H., Hirayu N., Takasu O., Hirohata M., Morioka M. Efficacy of a Novel Prophylactic Barbiturate Therapy for Severe Traumatic Brain Injuries: Step-down Infusion of a Barbiturate with Normothermia. Neurol Med Chir (Tokyo), 2021.
32
Kai K., Nasu K., Nishida H., Daa T., Shikama A., Shiozaki T., Kurakazu M., Yano M., Imamura Y., Tokunaga H., Tasaki K., Iida Y., Yamada Y., Morisawa H., Nakagawa S., Fujimoto E., Tsuruta T., Matsumoto H., Arakawa A., Nonaka M., Takano H., Ushiwaka T., Mori T., Ito K., Motohashi T., Teramoto N., Yamada T. Correlation of World Health Organization 2010 Classification for Gastroenteropancreatic Neuroendocrine Neoplasms with the Prognosis of Ovarian Neuroendocrine Neoplasms: Kansai Clinical Oncology Group-Protocol Review Committee/Intergroup Study. Neuroendocrinology, 111, 4, 320-329, 2021.
33
Jang J. H., Tomiyama Y., Miyazaki K., Nagafuji K., Usuki K., Uoshima N., Fujisaki T., Kosugi H., Matsumura I., Sasaki K., Kizaki M., Sawa M., Hidaka M., Kobayashi N., Ichikawa S., Yonemura Y., Enokitani K., Matsuda A., Ozawa K., Mitani K., Lee J. W., Nakao S. Efficacy and safety of romiplostim in refractory aplastic anaemia: a Phase II/III, multicentre, open-label study. Br J Haematol, 192, 1, 190-199, 2021.
34
Ito K., Yamanaka T., Hayashi H., Hattori Y., Nishino K., Kobayashi H., Oya Y., Yokoyama T., Seto T., Azuma K., Fukui T., Kozuki T., Nakamura A., Tanaka K., Hirano K., Yokoi T., Daga H., Sakata S., Fujimoto D., Mori M., Maeno K., Aoki T., Tamura A., Miura S., Watanabe S., Akamatsu H., Hataji O., Suzuki K., Hontsu S., Azuma K., Bessho A., Kubo A., Okuno M., Nakagawa K., Yamamoto N. Sequential therapy of crizotinib followed by alectinib for non-small cell lung cancer harbouring anaplastic lymphoma kinase rearrangement (WJOG9516L): A multicenter retrospective cohort study. Eur J Cancer, 145, 183-193, 2021.
35
Ishii H., Azuma K., Kawahara A., Matsuo N., Tokito T., Hoshino T. Atezolizumab plus carboplatin and etoposide in small cell lung cancer patients previously treated with platinum-based chemotherapy. Invest New Drugs, 39, 1, 269-271, 2021.
36
Hotta K., Nishio M., Saito H., Okamoto I., Nakahara Y., Hayashi H., Hayama M., Laud P., Jiang H., Paz-Ares L., Azuma K. First-line durvalumab plus platinum-etoposide in extensive-stage small-cell lung cancer: CASPIAN Japan subgroup analysis. Int J Clin Oncol, 26, 6, 1073-1082, 2021.
37
Hayashi K., Hiraoka K., Akiyama T., Iwata S., Tsuchiya H., Kawai A. Benefit of surgical resection of distant metastasis in soft tissue sarcoma: a systematic review. Jpn J Clin Oncol, 2021.
38
Furusawa A., Takekuma M., Mori K., Usami T., Kondo E., Nishio S., Nishino K., Miyamoto Y., Yoshimura R., Watanabe M., Mikami M., Enomoto T. A randomized phase III trial of adjuvant chemotherapy versus concurrent chemoradiotherapy for postoperative cervical cancer: Japanese Gynecologic Oncology Group study (JGOG1082). Int J Gynecol Cancer, 31, 4, 623-626, 2021.
39
Akamatsu H., Toi Y., Hayashi H., Fujimoto D., Tachihara M., Furuya N., Otani S., Shimizu J., Katakami N., Azuma K., Miura N., Nishino K., Hara S., Teraoka S., Morita S., Nakagawa K., Yamamoto N. Efficacy of Osimertinib Plus Bevacizumab vs Osimertinib in Patients With EGFR T790M-Mutated Non-Small Cell Lung Cancer Previously Treated With Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor: West Japan Oncology Group 8715L Phase 2 Randomized Clinical Trial. JAMA Oncol, 7, 3, 386-394, 2021.
40
Yoshida N., Miyoshi H., Arakawa F., Nakashima K., Kawamoto K., Seto M., Ohshima K. Cytokine-related genes play critical roles in extrafollicular growth of follicular lymphoma cells. Hematol Oncol, 38, 5, 673-679, 2020.
41
Yanagida E., Miyoshi H., Takeuchi M., Yoshida N., Nakashima K., Yamada K., Umeno T., Shimasaki Y., Furuta T., Seto M., Ohshima K. Clinicopathological analysis of immunohistochemical expression of CD47 and SIRPα in adult T-cell leukemia/lymphoma. Hematol Oncol, 38, 5, 680-688, 2020.
42
Watari K., Shibata T., Fujita H., Shinoda A., Murakami Y., Abe H., Kawahara A., Ito H., Akiba J., Yoshida S., Kuwano M., Ono M. NDRG1 activates VEGF-A-induced angiogenesis through PLCγ1/ERK signaling in mouse vascular endothelial cells. Commun Biol, 3, 1, 107, 2020.
43
Waki K., Yokomizo K., Kawano K., Tsuda N., Komatsu N., Yamada A. Integrity of plasma DNA is inversely correlated with vaccine-induced antitumor immunity in ovarian cancer patients. Cancer Immunol Immunother, 69, 10, 2001-2007, 2020.
44
Waki K., Kawano K., Tsuda N., Komatsu N., Yamada A. CD4/CD8 ratio is a prognostic factor in IgG nonresponders among peptide vaccine-treated ovarian cancer patients. Cancer Sci, 111, 4, 1124-1131, 2020.
45
Uchikado H., Nishimura Y., Hattori G., Ohara Y. Micro-anatomical structures of the lumbar intervertebral foramen for full-endoscopic spine surgery: review of the literatures. J Spine Surg, 6, 2, 405-414, 2020.
46
Tateishi T., Johkoh T., Sakai F., Miyazaki Y., Ogura T., Ichikado K., Suda T., Taguchi Y., Inoue Y., Takemura T., Colby T. V., Sumikawa H., Fujimoto K., Arakawa H., Raoof S., Inase N. High-resolution CT features distinguishing usual interstitial pneumonia pattern in chronic hypersensitivity pneumonitis from those with idiopathic pulmonary fibrosis. Jpn J Radiol, 38, 6, 524-532, 2020.
47
Tanoue S., Uchiyama Y., Hirohata M., Takeuchi Y., Orito K., Koganemaru M., Nagata S., Tanaka N., Abe T. Follow-up non-contrast MRA after treatment of intracranial aneurysms using microcoils with prominent metallic artifact: a comparative study of TOF-MRA and Silent MRA. Jpn J Radiol, 38, 9, 853-859, 2020.
48
Takeuchi M., Miyoshi H., Nakashima K., Kawamoto K., Yamada K., Yanagida E., Muta H., Moritsubo M., Umeno T., Suzuki T., Seto M., Ohshima K. Comprehensive immunohistochemical analysis of immune checkpoint molecules in adult T cell leukemia/lymphoma. Ann Hematol, 99, 5, 1093-1098, 2020.
49
Takekuma M., Takahashi F., Mabuchi S., Kudaka W., Horie K., Ikeda M., Shikama A., Mitsuhashi A., Nagao S., Suzuki S., Mizuno M., Nishio S., Tokunaga H., Ota Y., Kasamatsu T., Kitagawa R., Toita T., Kobayashi H., Ishikawa M., Yaegashi N. Propensity score-matched analysis of systemic chemotherapy versus salvage hysterectomy for persistent cervical cancer after definitive radiotherapy/concurrent chemoradiotherapy. BMC Cancer, 20, 1, 1169, 2020.
50
Takahama T., Azuma K., Shimokawa M., Takeda M., Ishii H., Kato T., Saito H., Daga H., Tsuboguchi Y., Okamoto I., Otsubo K., Akamatsu H., Teraoka S., Takahashi T., Ono A., Ohira T., Yokoyama T., Sakai K., Yamamoto N., Nishio K., Nakagawa K. Plasma screening for the T790M mutation of EGFR and phase 2 study of osimertinib efficacy in plasma T790M-positive non-small cell lung cancer: West Japan Oncology Group 8815L/LPS study. Cancer, 126, 9, 1940-1948, 2020.
51
Tahara N., Nitta Y., Bekki M., Tahara A., Maeda-Ogata S., Sugiyama Y., Honda A., Igata S., Nakamura T., Sun J., Kurata S., Fujimoto K., Abe T., Matsui T., Yamagishi S. I., Fukumoto Y. Two-hour postload plasma glucose and pigment epithelium-derived factor levels are markers of coronary artery inflammation in type 2 diabetic patients. J Nucl Cardiol, 27, 4, 1352-1364, 2020.
52
Suzuki T., Miyoshi H., Shimono J., Kawamoto K., Arakawa F., Furuta T., Yamada K., Yanagida E., Takeuchi M., Seto M., Sone H., Takizawa J., Ohshima K. Clinicopathological analysis of splenic red pulp low-grade B-cell lymphoma. Pathol Int, 70, 5, 280-286, 2020.
53
Shiraishi Y., Kishimoto J., Tanaka K., Sugawara S., Daga H., Hirano K., Azuma K., Hataji O., Hayashi H., Tachihara M., Mitsudomi T., Seto T., Nakagawa K., Yamamoto N., Okamoto I. Treatment Rationale and Design for APPLE (WJOG11218L): A Multicenter, Open-Label, Randomized Phase 3 Study of Atezolizumab and Platinum/Pemetrexed With or Without Bevacizumab for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer. Clin Lung Cancer, 21, 5, 472-476, 2020.
54
Shioga T., Kondo R., Ogasawara S., Akiba J., Mizuochi S., Kusano H., Mihara Y., Tanigawa M., Kinjyo Y., Naito Y., Kuromatsu R., Nakashima O., Yano H. Usefulness of Tumor Tissue Biopsy for Predicting the Biological Behavior of Hepatocellular Carcinoma. Anticancer Res, 40, 7, 4105-4113, 2020.
55
Shimada K., Yamaguchi M., Atsuta Y., Matsue K., Sato K., Kusumoto S., Nagai H., Takizawa J., Fukuhara N., Nagafuji K., Miyazaki K., Ohtsuka E., Okamoto M., Sugita Y., Uchida T., Kayukawa S., Wake A., Ennishi D., Kondo Y., Izumi T., Kin Y., Tsukasaki K., Hashimoto D., Yuge M., Yanagisawa A., Kuwatsuka Y., Shimada S., Masaki Y., Niitsu N., Kiyoi H., Suzuki R., Tokunaga T., Nakamura S., Kinoshita T. Rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with high-dose methotrexate plus intrathecal chemotherapy for newly diagnosed intravascular large B-cell lymphoma (PRIMEUR-IVL): a multicentre, single-arm, phase 2 trial. Lancet Oncol, 21, 4, 593-602, 2020.
56
Shibata T., Watari K., Kawahara A., Sudo T., Hattori S., Murakami Y., Izumi H., Itou J., Toi M., Akiba J., Akagi Y., Tanaka M., Kuwano M., Ono M. Targeting Phosphorylation of Y-Box-Binding Protein YBX1 by TAS0612 and Everolimus in Overcoming Antiestrogen Resistance. Mol Cancer Ther, 19, 3, 882-894, 2020.
57
Seto T., Azuma K., Yamanaka T., Sugawara S., Yoshioka H., Wakuda K., Atagi S., Iwamoto Y., Hayashi H., Okamoto I., Saka H., Mitsuoka S., Fujimoto D., Nishino K., Horiike A., Daga H., Sone T., Yamamoto N., Nakagawa K., Nakanishi Y. Randomized Phase III Study of Continuation Maintenance Bevacizumab With or Without Pemetrexed in Advanced Nonsquamous Non-Small-Cell Lung Cancer: COMPASS (WJOG5610L). J Clin Oncol, 38, 8, 793-803, 2020.
58
Sato M., Fuchida H., Shindo N., Kuwata K., Tokunaga K., Xiao-Lin G., Inamori R., Hosokawa K., Watari K., Shibata T., Matsunaga N., Koyanagi S., Ohdo S., Ono M., Ojida A. Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide-Pyrimidines. ACS Med Chem Lett, 11, 6, 1137-1144, 2020.
59
Sato K., Ono T., Sato F., Kawahara A., Azuma K., Kawaguchi T., Akiba J., Umeno H. Different responses to nivolumab therapy between primary and metastatic tumors in a patient with recurrent hypopharyngeal squamous cell carcinoma. Oral Oncol, 101, 104366, 2020.
60
Saku K., Tahara N., Takaseya T., Shintani Y., Takagi K., Shojima T., Kurata S., Fujimoto K., Abe T., Fukumoto Y., Tanaka H. Multimodal imaging of cardiac-calcified amorphous tumor. J Nucl Cardiol, 27, 2, 682-685, 2020.
61
Saku K., Tahara N., Takaseya T., Otsuka H., Takagi K., Shojima T., Shintani Y., Zaima Y., Kikusaki S., Fukuda T., Oryoji A., Nishino Y., Matsui T., Kakuma T., Akiba J., Fukumoto Y., Yamagishi S. I., Tanaka H. Pathological Role of Receptor for Advanced Glycation End Products in Calcified Aortic Valve Stenosis. J Am Heart Assoc, 9, 13, e015261, 2020.
62
Sakata K., Suematsu K., Takeshige N., Nagata Y., Orito K., Miyagi N., Sakai N., Koseki T., Morioka M. Novel method of intraoperative ocular movement monitoring using a piezoelectric device: experimental study of ocular motor nerve activating piezoelectric potentials (OMNAPP) and clinical application for skull base surgeries. Neurosurg Rev, 43, 1, 185-193, 2020.
63
Sakata K., Fujimori K., Komaki S., Furuta T., Sugita Y., Ashida K., Nomura M., Morioka M. Pituitary Gangliocytoma Producing TSH and TRH: A Review of “Gangliocytomas of the Sellar Region”. J Clin Endocrinol Metab, 105, 10, 3109-3121, 2020.
64
Renne S. L., Woo H. Y., Allegra S., Rudini N., Yano H., Donadon M., Viganò L., Akiba J., Lee H. S., Rhee H., Park Y. N., Roncalli M., Di Tommaso L. Vessels Encapsulating Tumor Clusters (VETC) Is a Powerful Predictor of Aggressive Hepatocellular Carcinoma. Hepatology, 71, 1, 183-195, 2020.
65
Onuki M., Matsumoto K., Iwata T., Yamamoto K., Aoki Y., Maenohara S., Tsuda N., Kamiura S., Takehara K., Horie K., Tasaka N., Yahata H., Takei Y., Aoki Y., Kato H., Motohara T., Nakamura K., Ishikawa M., Kato T., Yoshida H., Matsumura N., Nakai H., Shigeta S., Takahashi F., Noda K., Yaegashi N., Yoshikawa H. Human papillomavirus genotype contribution to cervical cancer and precancer: Implications for screening and vaccination in Japan. Cancer Sci, 111, 7, 2546-2557, 2020.
66
Ono T., Azuma K., Kawahara A., Kakuma T., Sato F., Kawaguchi T., Akiba J., Umeno H. Changes in immune parameters between pre-treatment and recurrence after (chemo) radiation therapy in patients with head and neck cancer. Sci Rep, 10, 1, 11973, 2020.
67
Ono T., Azuma K., Kawahara A., Kakuma T., Sato F., Akiba J., Tanaka N., Abe T., Chitose S. I., Umeno H. Predictive value of CD8/FOXP3 ratio combined with PD-L1 expression for radiosensitivity in patients with squamous cell carcinoma of the larynx receiving definitive radiation therapy. Head Neck, 42, 12, 3518-3530, 2020.
68
Onda T., Satoh T., Ogawa G., Saito T., Kasamatsu T., Nakanishi T., Mizutani T., Takehara K., Okamoto A., Ushijima K., Kobayashi H., Kawana K., Yokota H., Takano M., Kanao H., Watanabe Y., Yamamoto K., Yaegashi N., Kamura T., Yoshikawa H. Comparison of survival between primary debulking surgery and neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers in phase III randomised trial. Eur J Cancer, 130, 114-125, 2020.
69
Ogata S., Miyoshi H., Arakawa F., Shimono J., Yamada K., Yanagida E., Nambu M., Iwashita A., Haraoka S., Ohshima K. Clinicopathological features of in situ follicular neoplasm and relations with follicular lymphoma in Japan. Ann Hematol, 99, 2, 241-253, 2020.
70
Nishio S., Ushijima K. Clinical significance of primary debulking surgery and neoadjuvant chemotherapy-interval debulking surgery in advanced ovarian cancer. Jpn J Clin Oncol, 50, 4, 379-386, 2020.
71
Nishio S., Murotani K., Nakao S., Takenaka M., Suzuki S., Aoki Y., Todo Y., Hosaka M., Nakai H., Katabuchi H., Nishi H., Takekuma M., Mikami M., Enomoto T. Investigation of clinicopathological features of vulvar cancer in 1068 patients: A Japanese Gynecologic Oncology Group (JGOG) nationwide survey study. Gynecol Oncol, 159, 2, 449-455, 2020.
72
Nishio S., Matsumoto K., Takehara K., Kawamura N., Hasegawa K., Takeshima N., Aoki D., Kamiura S., Arakawa A., Kondo E., Hirakawa T., Yamamoto K., Aoki M., Stein K., Keefe S., Fujiwara K., Ushijima K. Pembrolizumab monotherapy in Japanese patients with advanced ovarian cancer: Subgroup analysis from the KEYNOTE-100. Cancer Sci, 111, 4, 1324-1332, 2020.
73
Nanri A., Katayama E., Imamura T., Muto I., Saruta H., Akiba J., Ohshima K., Nakama T., Ohata C. Cutaneous Histiocytic Sarcoma With Cellular Cannibalism. Am J Dermatopathol, 42, 4, 286-291, 2020.
74
Nakao S., Yamada S., Tsuda K., Yokomizo T., Sato T., Tanoue S., Hiraki T. Intrathecal administration of nusinersen for spinal muscular atrophy: report of three cases with severe spinal deformity. JA Clin Rep, 6, 1, 28, 2020.
75
Nakamura T., Morishige S., Ozawa H., Kuboyama K., Yamasaki Y., Oya S., Yamaguchi M., Aoyama K., Seki R., Mouri F., Osaki K., Okamura T., Mizuno S., Nagafuji K. Successful correction of factor V deficiency of patient-derived iPSCs by CRISPR/Cas9-mediated gene editing. Haemophilia, 26, 5, 826-833, 2020.
76
Nakagawa K., Hida T., Nokihara H., Morise M., Azuma K., Kim Y. H., Seto T., Takiguchi Y., Nishio M., Yoshioka H., Kumagai T., Hotta K., Watanabe S., Goto K., Satouchi M., Kozuki T., Koyama R., Mitsudomi T., Yamamoto N., Asakawa T., Hayashi M., Hasegawa W., Tamura T. Final progression-free survival results from the J-ALEX study of alectinib versus crizotinib in ALK-positive non-small-cell lung cancer. Lung Cancer, 139, 195-199, 2020.
77
Muta H., Sugita Y., Furuta T., Shiimura Y., Ohshima K., Nakashima K., Sato K., Morioka M., Abe H., Nozawa T., Fujii Y., Kakita A. Expression of the ghrelin/growth hormone secretagogue receptor axis and its functional role in promoting tumor growth in primary central nervous system lymphomas. Neuropathology, 40, 3, 232-239, 2020.
78
Murota M., Johkoh T., Lee K. S., Franquet T., Kondoh Y., Nishiyama Y., Tanaka T., Sumikawa H., Egashira R., Yamaguchi N., Fujimoto K., Fukuoka J. Influenza H1N1 virus-associated pneumonia often resembles rapidly progressive interstitial lung disease seen in collagen vascular diseases and COVID-19 pneumonia; CT-pathologic correlation in 24 patients. Eur J Radiol Open, 7, 100297, 2020.
79
Moritsubo M., Miyoshi H., Matsuda K., Yoshida N., Nakashima K., Yanagida E., Yamada K., Takeuchi M., Suzuki T., Muta H., Umeno T., Furuta T., Seto M., Ohshima K. TACC3 expression as a prognostic factor in aggressive types of adult T-cell leukemia/lymphoma patients. Int J Lab Hematol, 42, 6, 842-848, 2020.
80
Morishige S., Mizuno S., Ozawa H., Nakamura T., Mazahery A., Nomura K., Seki R., Mouri F., Osaki K., Yamamura K., Okamura T., Nagafuji K. CRISPR/Cas9-mediated gene correction in hemophilia B patient-derived iPSCs. Int J Hematol, 111, 2, 225-233, 2020.
81
Miyoshi H., Sato K., Kabeya Y., Yonezawa S., Nakano H., Takeuchi Y., Ozawa I., Higo S., Yanagida E., Yamada K., Kohno K., Furuta T., Muta H., Takeuchi M., Sasaki Y., Yoshimura T., Matsuda K., Muto R., Moritsubo M., Inoue K., Suzuki T., Sekinaga H., Ohshima K. Deep learning shows the capability of high-level computer-aided diagnosis in malignant lymphoma. Lab Invest, 100, 10, 1300-1310, 2020.
82
Miyoshi H., Sakata-Yanagimoto M., Shimono J., Yoshida N., Hattori K., Arakawa F., Yanagida E., Takeuchi M., Yamada K., Suzuki T., Moritsubo M., Furuta T., Chiba S., Ohshima K. RHOA mutation in follicular T-cell lymphoma: Clinicopathological analysis of 16 cases. Pathol Int, 70, 9, 653-660, 2020.
83
Miyamoto S., Azuma K., Ishii H., Bessho A., Hosokawa S., Fukamatsu N., Kunitoh H., Ishii M., Tanaka H., Aono H., Nakahara Y., Kusaka K., Hosomi Y., Kikuchi N., Mori Y., Itani H., Hamada A., Yamada K., Okamoto H. Low-Dose Erlotinib Treatment in Elderly or Frail Patients With EGFR Mutation-Positive Non-Small Cell Lung Cancer: A Multicenter Phase 2 Trial. JAMA Oncol, 6, 7, e201250, 2020.
84
Kusano H., Naito Y., Mihara Y., Kondo R., Ogasawara S., Akiba J., Nakashima O., Yano H. Distinctive clinicopathological features and KRAS and IDH1/2 mutation status of cholangiolocellular carcinoma. Hepatol Res, 50, 1, 84-91, 2020.
85
Kurose H., Ueda K., Uegaki M., Ogasawara N., Kumagae H., Chikui K., Nakiri M., Nishihara K., Matsuo M., Suekane S., Akiba J., Yano H., Igawa T. Paraganglioma of the urinary bladder: Case report and literature review. IJU Case Rep, 3, 5, 192-195, 2020.
86
Kunitake T., Kakuma T., Ushijima K. Risk factors for lower limb lymphedema in gynecologic cancer patients after initial treatment. Int J Clin Oncol, 25, 5, 963-971, 2020.
87
Kukimoto I., Matsumoto K., Takahashi F., Iwata T., Tanaka K., Yamaguchi-Naka M., Yamamoto K., Yahata H., Nakabayashi M., Kato H., Tsuda N., Onuki M., Yaegashi N. Human Papillomavirus (HPV) Genotyping Assay Suitable for Monitoring the Impact of the 9-Valent HPV Vaccine. Tohoku J Exp Med, 251, 4, 287-294, 2020.
88
Kondoh Y., Azuma A., Inoue Y., Ogura T., Sakamoto S., Tsushima K., Johkoh T., Fujimoto K., Ichikado K., Matsuzawa Y., Saito T., Kishi K., Tomii K., Sakamoto N., Aoshima M., Araya J., Izumi S., Arita M., Abe M., Yamauchi H., Shindoh J., Suda T., Okamoto M., Ebina M., Yamada Y., Tohda Y., Kawamura T., Taguchi Y., Ishii H., Hashimoto N., Abe S., Taniguchi H., Tagawa J., Bessho K., Yamamori N., Homma S. Thrombomodulin Alfa for Acute Exacerbation of Idiopathic Pulmonary Fibrosis. A Randomized, Double-Blind Placebo-controlled Trial. Am J Respir Crit Care Med, 201, 9, 1110-1119, 2020.
89
Kojima S., Hisaka T., Midorikawa R., Naito Y., Akiba J., Tanigawa M., Yano H., Akagi Y., Okuda K. Prognostic Impact of Desmoplastic Reaction Evaluation for Intrahepatic Cholangiocarcinoma. Anticancer Res, 40, 8, 4749-4754, 2020.
90
Kazama R., Miyoshi H., Takeuchi M., Miyawaki K., Nakashima K., Yoshida N., Kawamoto K., Yanagida E., Yamada K., Umeno T., Suzuki T., Kato K., Takizawa J., Seto M., Akashi K., Ohshima K. Combination of CD47 and signal-regulatory protein-α constituting the “don’t eat me signal” is a prognostic factor in diffuse large B-cell lymphoma. Cancer Sci, 111, 7, 2608-2619, 2020.
91
Kawano K., Yamaguchi T., Nasu H., Nishio S., Ushijima K. Subcategorization of atypical glandular cells is useful to identify lesion site. Diagn Cytopathol, 48, 12, 1224-1229, 2020.
92
Kawaguchi T., Ikuta K., Tatsumi Y., Toki Y., Hayashi H., Tonan T., Ohtake T., Hoshino S., Naito M., Kato K., Okumura T., Torimura T. Identification of heterozygous p.Y150C and p.V274M mutations in the HJV gene in a Japanese patient with a mild phenotype of juvenile hemochromatosis: A case report. Hepatol Res, 50, 1, 144-150, 2020.
93
Kanno H., Miyoshi H., Yoshida N., Sudo T., Nakashima K., Takeuchi M., Nomura Y., Seto M., Hisaka T., Tanaka H., Okuda K., Akagi Y., Ohshima K. Differences in the immunosurveillance pattern associated with DNA mismatch repair status between right-sided and left-sided colorectal cancer. Cancer Sci, 111, 8, 3032-3044, 2020.
94
Kaji D., Ota Y., Sato Y., Nagafuji K., Ueda Y., Okamoto M., Terasaki Y., Tsuyama N., Matsue K., Kinoshita T., Yamamoto G., Taniguchi S., Chiba S., Ohshima K., Izutsu K. Primary human herpesvirus 8-negative effusion-based lymphoma: a large B-cell lymphoma with favorable prognosis. Blood Adv, 4, 18, 4442-4450, 2020.
95
Kaida H., Azuma K., Kawahara A., Takamori S., Akiba J., Fujimoto K., Ishii K., Ishibashi M. Prognostic value of dual-point fluorine-18 fluorodeoxyglucose PET imaging, partial volume correction and glucose transporter-1 expression in resected nonsmall cell lung cancer patients. Nucl Med Commun, 41, 1, 48-57, 2020.
96
Iwata S., Kawai A., Ueda T., Ishii T., Japanese Musculoskeletal Oncology Group. Symptomatic Venous Thromboembolism in Patients with Malignant Bone and Soft Tissue Tumors: A Prospective Multicenter Cohort Study. Ann Surg Oncol, 2020.
97
Ito H., Watari K., Shibata T., Miyamoto T., Murakami Y., Nakahara Y., Izumi H., Wakimoto H., Kuwano M., Abe T., Ono M. Bidirectional Regulation between NDRG1 and GSK3β Controls Tumor Growth and Is Targeted by Differentiation Inducing Factor-1 in Glioblastoma. Cancer Res, 80, 2, 234-248, 2020.
98
Ishii H., Azuma K., Sakai K., Naito Y., Matsuo N., Tokito T., Yamada K., Hoshino T., Nishio K. Determination of Somatic Mutations and Tumor Mutation Burden in Plasma by CAPP-Seq during Afatinib Treatment in NSCLC Patients Resistance to Osimertinib. Sci Rep, 10, 1, 691, 2020.
99
Ishii H., Azuma K., Kawahara A., Kinoshita T., Matsuo N., Naito Y., Tokito T., Yamada K., Akiba J., Hoshino T. Predictive value of CD73 expression for the efficacy of immune checkpoint inhibitors in NSCLC. Thorac Cancer, 11, 4, 950-955, 2020.
100
Hisaka T., Sakai H., Sato T., Goto Y., Nomura Y., Fukutomi S., Fujita F., Mizobe T., Nakashima O., Tanigawa M., Naito Y., Akiba J., Ogasawara S., Nakashima K., Akagi Y., Okuda K., Yano H. Quercetin Suppresses Proliferation of Liver Cancer Cell Lines In Vitro. Anticancer Res, 40, 8, 4695-4700, 2020.
101
Himuro H., Kurata S., Nagata S., Sumi A., Tsubaki F., Matsuda A., Fujimoto K., Abe T. Imaging features in patients with SAPHO/CRMO: a pictorial review. Jpn J Radiol, 38, 7, 622-629, 2020.
102
Heng M., Gupta A., Chung P. W., Healey J. H., Vaynrub M., Rose P. S., Houdek M. T., Lin P. P., Bishop A. J., Hornicek F. J., Chen Y. L., Lozano-Calderon S., Holt G. E., Han I., Biau D., Niu X., Bernthal N. M., Ferguson P. C., Wunder J. S. The role of chemotherapy and radiotherapy in localized extraskeletal osteosarcoma. Eur J Cancer, 125, 130-141, 2020.
103
Fukunaga S., Mori A., Ohuchi A., Yoshioka S., Akiba J., Mistuyama K., Tsuruta O., Torimura T. Gastrointestinal: Abdominal pain, diarrhea, and bloody stools in a patient treated for renal cell carcinoma with sunitinib. J Gastroenterol Hepatol, 35, 1, 10, 2020.
104
Fukuhara T., Saito H., Furuya N., Watanabe K., Sugawara S., Iwasawa S., Tsunezuka Y., Yamaguchi O., Okada P. M., Yoshimori K., Nakachi I., Gemma P. A., Azuma K., Kurimoto F., Tsubata Y., Fujita Y., Nagashima H., Asai G., Watanabe S., Miyazaki M., Hagiwara P. K., Nukiwa P. T., Morita P. S., Kobayashi P. K., Maemondo P. M. Evaluation of plasma EGFR mutation as an early predictor of response of erlotinib plus bevacizumab treatment in the NEJ026 study. EBioMedicine, 57, 102861, 2020.
105
Endo H., Tanoue S., Hiramatsu M., Matsumoto Y., Sato K., Sato M., Matsumaru Y., Tsuruta W., Kiyosue H. Risk factors for medullary infarction after endovascular trapping of vertebral artery dissecting aneurysms. Neurosurg Rev, 2020.
106
Bekki M., Tahara N., Tahara A., Maeda-Ogata S., Sugiyama Y., Honda A., Igata S., Harada A., Hirakawa Y., Kurata S., Fujimoto K., Abe T., Fukumoto Y., Ueno T. Switching from clopidogrel to prasugrel resolves vascular inflammation in patients receiving long-term aspirin plus clopidogrel therapy after coronary stent implantation. J Nucl Cardiol, 2020.
107
Akiba J., Fujita N., Yano H. Recent Topics Concerning Combined Hepatocellular Cholangiocarcinoma. Kurume Med J, 66, 1, 29-36, 2020.
108
Akashi M., Yamaguchi R., Kusano H., Ogasawara S., Abe E., Obara H., Yamaguchi M., Akiba J., Kakuma T., Tanaka M., Akagi Y., Yano H. Androgen receptor expression is useful to predict the therapeutic effect in HER2-positive breast carcinoma. Breast Cancer Res Treat, 184, 2, 277-285, 2020.
109
Akashi M., Yamaguchi R., Kusano H., Obara H., Yamaguchi M., Toh U., Akiba J., Kakuma T., Tanaka M., Akagi Y., Yano H. Diverse histomorphology of HER2-positive breast carcinomas based on differential ER expression. Histopathology, 76, 4, 560-571, 2020.